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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'f8b95f3e81a7a9276796e40d16d321dc4e0628ba055e183aa6320b5a665b8a4b' 
  AND token = 'OsT9a76yKvwEbCvhKX2mti+EiS+/KCg4/ZbJvjmEH4c=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00022

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}