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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '0678439b1bc0b49f0b29a30cd9884971e61ecb9eccbd75c10de176fdfc86d5e3' 
  AND token = '5PN2Bwa3Mj4rs4wuvJqc7DsYP2dcFJ60Fiv4r1KiggE=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00018

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}