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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'b497ac5953686e81e6d29c526fdde59d481a582e32a2ea2740ad8040629838eb' 
  AND token = 'LiFpOgv9ESaA62I3eX0xUReEL2+mGnMAfESlCdH9DIw=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00021

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}