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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'ecc286d7183a2997c00cf21f78efadde7c86ca81d3c38e72c523d38731855527' 
  AND token = '48GXg7kxD2bnviYNRIaD2gwMDfpxq/jyqLB3FRFj10I=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00024

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}