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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'b28aabd674a82387e001f2fa4b9f8faf8dd8e54f81f567266d4097f17a56f9f2' 
  AND token = 'GuCTq+gYK6iEQ4kMCls0nj7pkEuw9w2NZbwrezcloxs=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00015

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}