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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '8273982676647e1f7094b09d139d9d5b007a56bfcf887f660278a0f1f55ec73a' 
  AND token = 'RBDtciUs+e8MmuZE+yrE3d9yXldadCLaaGXJLAMiseM=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00018

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}