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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '899cd14c3ae6961a9c15ca8319160054f70e01e2357f3d9f4ed2acc7e87c8b83' 
  AND token = 'Pe1k6XQQAyyua1ux7PyMaOVumt2nI/Uy4cB5B+46bnk=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00018

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}