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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '6fab3adbd4c07144d5b34d53aeef9b8a19a0ea6a0622f03b5e0bb8be82e2de9f' 
  AND token = 'IZbkjzTx+YZA3STBLnscEo8GzknSauwNnCD3QPpl9UM=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00017

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}