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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'ef2ee72ddde29ccefecbbca70ad8770d1c0f1f210af6aa35b44bec10edbba044' 
  AND token = 'vvJ/MZODN3DTPNoyWhzdOq1SIbzSN9QyM8hkiooORIA=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00019

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}