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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '3d36d340011d71efb17b2f0c141d6eba9506b54eea1bbb07e8461a6da7b3589e' 
  AND token = 'RXrfZQobj3EzYO5yuva4NcWuQrIyFIsbwGivqmE1M4M=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00021

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}