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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '2abf7e8cf60f63b9129854efdfe7a2fb7dcbde3f05157bb1a5dbd28a23b1587f' 
  AND token = 'QPEaxzu7/17o7rijuSVKhtm9pIf5klZLu1kW29WKYv0=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00020

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}