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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'fff8111c561db5e7b38914190b7ca9e441ee4054308d92507d22d88a6d615533' 
  AND token = '2UJHRDZgbGdI5FM/vt/a6fdhkCFg8unK56Eden1UBdI=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00018

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}