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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '6be267c0e054937ebcb4be3d554f6a059698d2b05303f7f0d5bbf861478e9b38' 
  AND token = 'nFOoRAPwgglE4FJt+MF3yXuZ68WcOBwB92zTKPjiAt0=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00024

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}