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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'ed8e47e5f64bfe8eb94c429a436f4b09bbe74030301e21ca5b68b1c86cdafbfc' 
  AND token = 'b7VUXZ3XOzFTeJyyWE7kSGK0rIkPu7zfjQxI322wsR8=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00018

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}