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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '789261dcdc3584fffb849b784fa17dbbb459edfb898da025239ed94d0e659f02' 
  AND token = '48Ynxeij0xQlRnR25na7oi2zBxzIYEAOAfn8jgq4KyY=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00019

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}