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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '44ca55647285a4d995df8478d0b949306bc45e6fdbc5e5359bb6910445dc2c71' 
  AND token = 'fmz349qvRikEQI5xKTlKjvpEjqmJP0uZvDvLnP35T7U=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00017

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}