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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'c0808d05be4766829f41c8cff31dd2518e1dcc6c08d6457e0c7014c8323e3d99' 
  AND token = 'TDpcXM1kOgwqyfUq8nu9ybIiGIqc2dDV+o/vwsV78ZE=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00021

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}