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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'e8ad8b1c87d195b18065ea445e98c84ad20e9776f58bd3d33695d0c28fa2afd8' 
  AND token = 'HSJYC8wCZWLCG7+G16CCyzTlUED5mlekVasKWd9bQeo=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00018

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}