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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '22a9ec77d71fea95be0c4428ef2bfb25ba4a879cb46018ce06aebf7244642d94' 
  AND token = 'v50cyMZNA0nTR53KAl0tnFLz5vcclaiPMSICzuB6YTk=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00018

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}