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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'b118152bb7476fa0a929e7a617f6d3cbf57e9fecba355a5dfd0e2e2200e8f08e' 
  AND token = 'FXR/gFOPcQRiO8XzL0w7m9rKCQFPVTZ+9U33z2M0AuI=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00019

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}