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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '0f0845ef066425fcd847fa8ec61945b9e3c3e69995a71fabea3fab1872b3fee2' 
  AND token = 'B5bUtr1DHFyK5IJyO754zOVxvYosKmHcStw/cl9dYoA=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00020

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}