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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '2f5b8d0bbe440bb975c215ecbc30b314567802e22f8fbd7fa70536b9dd01a8d1' 
  AND token = '58Uyn+72957imGBY+sNjNscU472LXJSBobEX6bU1AAQ=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00018

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}