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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '40445ddfa1039fdc3acdd4ec89417afa20ea8c07647fa84e93e39dda078d6e81' 
  AND token = 'yNTdMWUIG6uFkRr07I3+G4Ypowk+VhMcJFfqoTJXNs0=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00019

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}