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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '46e7bf62b4b81b499f506d5388aca5ca1a90207ad24a70e67dd5e48b13013958' 
  AND token = 'yl6A5H6denyeolzLAt9qdn/ZIhDFJlV4TFhZ7aR+daw=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00022

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}