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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'a187b73bd98f535c69de350ae55262ea09d5872ab3462412ec6f07ec636ba498' 
  AND token = '9O4neFZwNe/x8yfxmRZMdT6sEaH7gaeOt/YPDwQyFNY=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00018

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}