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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '72c417543d84a96ea811a637b19b37e70bc3323070c823ea3b88a27b979d4874' 
  AND token = 'pILBz9gFYXN/Ra2PFhK64/3RkXOxdmW3/5YgK3h6UZg=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00029

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}