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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '4caeb9eadf0e4be9b62f7803f7af84ed7b40835f24865428edc0849b3c486011' 
  AND token = 'u4wE1GK4/jaf00NOEVXLJs6Xy8b8zeCimSqP74q2pgk=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00020

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}