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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '6ea2eb33af70d6235c7bee3df4a13789917110c0b870cd7e4dc9c813ab4147d2' 
  AND token = 'ba751v2BuefQTBboIuGdIMvb5Ip0wRHuR3QQ5PFYEsc=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00021

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}