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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'c789531287021526a894fc9ae9f9e9878d62ffbdac0ced463cb64fc7abc323e6' 
  AND token = 'mRSE7EXQobVWjxe4lLHzdh+L9fB9rsw4JVsvWc1ocbY=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00017

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}