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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '5fc264fb5d210685e537d78a77042ab04e7d97fdc72e32e3063c7259d31d603b' 
  AND token = 'P9tcdEPUbMk1yB0YhN8hmxjfWI+2XdFKE0ElFFU+1aQ=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00021

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}