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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '579578df6fe02f321fa4e6b78b2a6ec317033a3e444e60848c53a2acbb0424dd' 
  AND token = 'R87J/r6FbbK9FlScDnnJ6aWXtTIqHuSCyzoqeOSDwPw=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00020

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}