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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'b3f2d9f71a16f8843868fcf5151328b2b735057c1d71946230277ede71ff60b2' 
  AND token = 'uK6VIE7IWq9W8TijaGXrzf8HGZpTPoyXDt5/lV1sILI=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00028

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}