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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'f658d7c4887f9f42632b80ffb00b4324a6490f2e19a32ca062061971a0339290' 
  AND token = 'MNO4j0fjcQYl+DMVAEH1fFtzi52eUMde1PE5kf/onzU=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00022

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}