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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'e235214858b890ceaf1b679bb2ab5e479d79aad8497aac9ab9c13e10f801d506' 
  AND token = 'q5ix39ABHCQ0xd6+85fl8YRxdOxSrVEcJiHTOPOdLFE=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00017

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}