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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '27bf136e93744e5e9dc6b4883dd3b2dfada164d07148bf944817865f7e47a93d' 
  AND token = 'pwPvOiNaR+s69J2eh7INDEnWCfG0Tefi/41i73XvD2c=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00023

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}