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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '184bd4b58aa1efde041f3fdbc7d346f137fca6135b0dd05a5986dfcda2a74ad7' 
  AND token = 'R1CpZ9xIk7L+ArbQR1F5NgXcTEPyuAUh6P/VF7l2YCw=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00020

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}