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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '21617550f4b7448944cb5c85bba0661bfb58f0a000c5485be4cf7d74d7f8a275' 
  AND token = 'QA8PHlwEfstL/o0uEgSh9nS4V+4aMY5h4y0bBwiUj10=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00017

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}