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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '331f725bd674802f33397c290310375d75c085d2b4301b6dd02bc2ac7323193f' 
  AND token = 'yi0oICq3hFAc94y00BtT50aL+/XoNQ0ZYlOehN7Sf2g=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00017

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}