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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '2ad4940ff30901e47aed2919667684e2aa99d4a949bc79f27fa062a0c5528cf6' 
  AND token = '2EHO9UY42IoZVDaO1piA5rkKTGGuM9xgd7BpXa+5TWU=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00025

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}