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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'a16488fc511842d93a36bff5d5a08ee05b2bc34a85a8a94276433eaf816bb1f8' 
  AND token = '9C0ukPC8fPdbBjWZ1xuWQtZblONdXCY9U0IWm7GHU5Q=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00019

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}