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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '282191d73a1d8bce1ee83f5beb563fb203d7729201be4dfac11f854b5d7515cb' 
  AND token = 'M6fpt7XdBZdjbothObdQQ930+Irmb8sd75bd50jveMI=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00017

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}