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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'fc50f9ab921926923a194cb7a896061327b04619e2df2244b1f8e00a8b62fd8c' 
  AND token = '14JJ7xmOYaWcjB0FotaNAnYNTTrbdYQ1mhk26BtfjQw=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00019

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}