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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'd9f9ad3956902e2c45dabb5c4bb72c694c3bb780d8f21272fa6b46c6628093e8' 
  AND token = 'b4g86xMRMFxGP2nN25OxRhUki5FYpas5+VHeFtP860Y=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00020

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}