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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'd0a34c2b3a1371c760dddc88303adb8fa18d60fa6ee047cee2957a64b4faf375' 
  AND token = 'D7YOC6a8qlKI+r8brKgjj4NNduoXjhwDCtSeYiRVM2c=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00024

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}