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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'ecaf7af99364d0667064d4dc1a54b7b3879bf34498e8c7fd0ba12b5a49c5854d' 
  AND token = '/3DeEy033PZL7f2zRgts45iISVlNErr73dHitwhKCmY=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00018

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}