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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'e850194abc21adca649ca3d155570fc24d6228e1f1f7e16a5cf26aeac32b122c' 
  AND token = 'Ts+VNM7sPxqAfsDjV779+2DdsEHxj2Tm/zaqMembAi8=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00017

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}