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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '7371e9d80f54ae654a268ae621eae4219b9d40b3e33302a05c388459fc0dc24f' 
  AND token = 'UxTAsaFIo0PJgYqxyFM2fN9dkEVQd2XBRUjF0Ehpv68=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00018

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}