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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '134c3a3d7478a244bf69cd79a8ccfc3318365675b14229ca1b87a546187413c1' 
  AND token = '9Pf4YOAUMhdihOLcC2X1toP+lLB1ejqoNI1YQo4CHHs=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00018

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}