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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'bf72792566d4406a5a027b3b7b05da87cf3ae3918f9d4e4817d4d0017f0b0b1e' 
  AND token = 'tYiUXuSlVpQlhrQ88g7aOEWSbTORYNeOhdqagJUob1I=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00022

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}