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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'e0a1ceddaeead89f3f721687ebb68df46d0e86f8bbad5b9899799ab10698584b' 
  AND token = 'd108Cu+8dHt757RsRk3qGdyguusGT6N5NUb4lmw0rXk=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00018

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}